I took care to make the letters large and be generous with character and line spacing in order for it to be easy to read for the elderly and those who have problems with their sight

He tried to find out what he was up against

The pioneers have overcome a series of obstacles

Lack of money is a serious hindrance in their fight to conquer cancer

Birds sometimes cause accidents by getting in the way of airplanes

Lack of flexibility is an obstacle to one's progress

He went forward in the face of many obstacles

His loss of memory is a psychological problem rather than a physical one